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1) Costanzo M, Romeo A, Cisterna B, Calderan L, Bernardi P, Covi V, Tabaracci G, Malatesta M
Ozone at low concentrations does not affect motility and proliferation of cancer cells in vitro.
Eur J Histochem. 2020 Apr 2;64(2):3119. doi: 10.4081/ejh.2020.3119.
2) Tricarico G, Rodrigues Orlandin J, Rocchetti V, Ambrosio CE, Travagli V.
A critical evaluation of the use of ozone and its derivatives in dentistry.
Eur Rev Med Pharmacol Sci. 2020 Sep;24(17):9071-9093. doi: 10.26355/eurrev_202009_22854.
3) Cisterna B, Costanzo M, Nodari A, Galiè M, Zanzoni S, Bernardi P, Covi V, Tabaracci G, Malatesta M.
Ozone Activates the Nrf2 Pathway and Improves Preservation of Explanted Adipose Tissue In Vitro.
Antioxidants (Basel). 2020 Oct 14;9(10):989. doi: 10.3390/antiox9100989.
4) Travagli V
The right therapeutic method of ozone therapy used to treat multiple sclerosis patients.
Mult Scler Relat Disord. 2020 Nov;46:102545. doi: 10.1016/j.msard.2020.102545. Epub 2020 Sep 29.
5) Bonetti M, Zambello A, Princiotta C, Pellicanò G, Della Gatta L, Muto M.
Non-discogenic low back pain treated with oxygen-ozone: outcome in selected applications.
J Biol Regul Homeost Agents. 2020 Jul-Aug;34 (4 Suppl. 1):21-30.
6) Marini S, Maggiorotti M, Dardes N, Bonetti M, Martinelli M, Re L, Carinci F, Tavera C.
Oxygen-ozone therapy as adjuvant in the current emergency in SARS-COV-2 infection: a clinical study.
Promoter of the study: NUOVA F.I.O. (Italian Oxygen-Ozone Federation);
J Biol Regul Homeost Agents. 2020 May-Jun;34(3):757-766. doi: 10.23812/20-250-E-56.
7) Della Gatta L, Guarnieri G, Ambrosanio G, Capobianco E, Muto M.
Clinical and imaging selection for CT guided – fluoroscopy 0203 disk treatment.
J Biol Regul Homeost Agents. 2020 Jul-Aug;34(4 Suppl. 1):15-19.
8) Alexandre A, Zalaffi A
Electromyographic analysis of the results given by lumbar discal herniation treatment with intradiscal oxygen-ozone gas mixture injection.
J Biol Regul Homeost Agents. 2020 Jul-Aug;34(4 Suppl. 1):57-61.
9) Moreo G, Mucchi D, Carinci F.
Efficacy ozone therapy in reducing oral infection of periodontal disease: a randomized clinical trial.
J Biol Regul Homeost Agents. 2020 Jul-Aug;34(4 Suppl. 1):31-36.
10) Martinelli M, Giovannangeli F, Venditto T, Travagli V.
The use of oxygen ozone therapy in the treatment of cervicobrachial pain: case series study.
J Biol Regul Homeost Agents. 2020 Jul-Aug;34(4 Suppl. 1):47-55.
11) Re L, Noci JB, Gadelha Serra ME, Mollica P, Bonetti M, Travagli V.
Safety, pitfalls, and misunderstandings about the use of ozone therapy as a regenerative medicine tool. A narrative review.
J Biol Regul Homeost Agents. 2020 Jul-Aug;34(4 Suppl. 1):1-13
12) M. Bonetti, G.M. Ottaviani, A. Fontana, G. Pellicanò, L. Della Gatta, M. Muto
Diagnosis and subsequent treatment with oxygen-ozone therapy of Baastrup’s disease
European Journal of Musculoskeletal Diseases 2020; 9(2) Jul-Dec: e00002
13) Tricarico G, Isakovic J, Song MS, Rustichelli F, Travagli V, Mitrecic D.
Ozone influences migration and proliferation of neural stem cells in vitro.
Neurosci Lett. 2020 Nov 20;739:135390. doi: 10.1016/j.neulet.2020.135390. Epub 2020 Sep 15.
14) Tascini C, Sermann G, Pagotto A, Sozio E, De Carlo C, Giacinta A, Sbrana F, Ripoli A, Castaldo N, Merelli M, Cadeo B, Macor C, De Monte A.
Blood ozonization in patients with mild to moderate COVID-19 pneumonia: a single centre experience.
Intern Emerg Med. 2021 Apr;16(3):669-675. doi: 10.1007/s11739-020-02542-6. Epub 2020 Nov 1.
15) De Monte A, Sermann G, Sozio E, Sbrana F, Tascini C.
Blood ozonization in patients with mild to moderate COVID-19 pneumonia: a single centre experience: reply.
Intern Emerg Med. 2021 Apr;16(3):795-796. doi: 10.1007/s11739-021-02630-1. Epub 2021 Feb 3.
16) Bonetti M, Travagli V.
Gaseous ozone or method of administration: Hunt for the culprit.
Am J Emerg Med. 2021 Mar;41:256. doi: 10.1016/j.ajem.2020.05.110. Epub 2020 Jun 3.
17) Zambello A, Bonetti M.
OZONOTERAPIA. Manuale pratico
Edizioni Fedan SA, Lugano (Switzerland). 2021
18) Orlandin JR, Machado LC, Ambrósio CE, Travagli V.
Ozone and its derivatives in veterinary medicine: A careful appraisal.
Vet Anim Sci. 2021 Jul 28;13:100191. doi: 10.1016/j.vas.2021.100191. eCollection 2021 Sep.
19) Leone G, Muto Mas., Guarnieri G, Della Gatta L, Bonetti M, Muto Mar.
Minimally Invasive Treatment of Herniated Disc: How to Remove the Disc with Chemical Tool
The Disc and Degenerative Disc Disease pp 173-184. Ed Springer 2021
20) Sozio E, De Monte A, Sermann G, Bassi F, Sacchet D, Sbrana F, Ripoli A, Curcio F, Fabris M, Marengo S, Italiani D, Luciana Boccalatte-Rosa D, Tascini C; CORMOR study Group.Int CORonavirus-19 mild to moderate pneumonia Management with blood Ozonization in patients with Respiratory failure (CORMOR) multicentric prospective randomized clinical trial.
Immunopharmacol. 2021 Sep;98:107874. doi: 10.1016/j.intimp.2021.107874. Epub 2021 Jun 12.
21) G. Tabaracci, G. Bragaglio, G. Guarino, I. Marchina, M. Bonetti
Resolution of a case of post-traumatic elbow bursitis with oxygen-ozone therapy
European Journal of Musculoskeletal Diseases 2021; 10(2) May-August, e0004
22) Rimeika G, Saba L, Arthimulam G, Della Gatta L, Davidovic K, Bonetti M, Franco D, Russo C, Muto M.Metanalysis on the effectiveness of low back pain treatment with oxygen-ozone mixture: Comparison between image-guided and non-image-guided injection techniques,
Eur J Radiol Open 2021 Dec 6;8: 100389.
doi: 10.1016/j.ejro.2021.100389.
23) Tricarico G, Travagli V.
The Relationship between Ozone and Human Blood in the Course of a Well-Controlled, Mild, and Transitory Oxidative Eustress.
Antioxidants (Basel). 2021 Dec 4;10(12):1946. doi: 10.3390/antiox10121946.
24) Re L, Rutledge DK, Erario A, Baeza-Noci J, Travagli V, Menendez S, Mollica PJ
Correcting Misinformation about the Science and Practice of Evidence-Based, Safe and Effective Ozone Therapy.
J Emerg Med. 2021 Dec;61(6):799-800. doi: 10.1016/j.jemermed.2021.08.001. Epub 2021 Oct 6.
25) M.Bonetti, D.Lauritano, GM Ottaviani, A Fontana, A.Zambello, L Della Gatta, M. Muto, F Carinci.
Oxygen -Ozone Therapy Associated with Alpha Lipoic Acid
Plus Palmitoylethanolamide and Myrrh versus Ozone Therapy in the Combined Treatment of Sciatic Pain Due to Herniated Discs: Observational Study on 318 Patients
Int. J. Environ. Res. Public Health 2022, 19 (9), 5716
https://doi.org/10.3390/ijerph19095716 – 07 May 2022
26) M. Bonetti, G. Bragaglio, G. Guarino, I. Marchina, G. Ottaviani, and M. Moretti
Calcific post-epidural steroid infiltration epiduritis, when and if to treat with ozone therapy
European Journal of Musculoskeletal Diseases 2022; 11(2) May-August, e0004
27) Travagli V.
Some clarifications regarding ozone therapy vs retinal vascular reactivity.
Photodiagnosis Photodyn Ther. 2022 Dec;40:103140. doi: 10.1016/j.pdpdt.2022.103140. Epub 2022 Oct 1
28) M. Bonetti, G. Bragaglio, G. Guarino, I. Marchina, G. Ottaviani, M. Moretti and A. Majorana
CT guided infiltration of the TMJ with oxygen-ozone in temporomandibular joint osteoarthrosis. Our experience
European Journal of Musculoskeletal Diseases 2022; 11(2) May-August, e00011
29) Malatesta M, Cisterna B, Costanzo M.
Cellular and Molecular Mechanisms of Ozone Therapy: Present Knowledge and Prospective Applications.
Int J Mol Sci. 2022 Oct 20;23(20):12586. doi: 10.3390/ijms232012586.
30) Cisterna B, Costanzo M, Lacavalla MA, Galiè M, Angelini O, Tabaracci G, Malatesta M.
Low Ozone Concentrations Differentially Affect the Structural and Functional Features of Non-Activated and Activated Fibroblasts In Vitro.
Int J Mol Sci. 2021 Sep 20;22(18):10133. doi: 10.3390/ijms221810133.
31) Lacavalla MA, Inguscio CR, Cisterna B, Bernardi P, Costanzo M, Galiè M, Scambi I, Angelini O, Tabaracci G, Malatesta M.
Ozone at low concentration modulates microglial activity in vitro: A multimodal microscopy and biomolecular study.
Microsc Res Tech. 2022 Dec;85(12):3777-3792. doi: 10.1002/jemt.24233. Epub 2022 Sep 21.
32) M Bonetti
Back pain “not just herniated disc”: results of treatment with oxygen-ozone therapy in selected applications.
Journal of Ozone Therapy (JO3T), 2022 – dialnet.unirioja.es
33) M. Bonetti, D. Lauritano, GM. Ottaviani, A. Fontana, M.Frigerio, A Zambello, L. Della Gatta, M. Muto and F.Carinci
New Approach to Chronic Back Pain Treatment: A Case
Control Study
Biomedicines 2023, 11, 73. https://doi.org/10.3390/biomedicines11010073
34) Pasek J, Szajkowski S, Travagli V, Cieślar G.
Topical Hyperbaric Oxygen Therapy Versus Local Ozone Therapy in Healing of Venous Leg Ulcers.
J Environ Res Public Health. 2023 Jan 20;20(3):1967. doi: 10.3390/ijerph20031967.
35) Alexandre, S. John and A.M. Alexandre
Intradiscal injection of oxygen-ozone gas mixture for the treatment of contained cervical disc herniations
Eur J Musculoskel Dis 2023 Jan-Apr; 12(2): 51-56
36) Travagli V, Iorio EL.
The Biological and Molecular Action of Ozone and Its Derivatives: State-of-the-Art, Enhanced Scenarios, and Quality Insights.
Int J Mol Sci. 2023 May 9;24(10):8465. doi: 10.3390/ijms24108465.
37) Inguscio CR, Dalla Pozza E, Dando I, Boschi F, Tabaracci G, Angelini O, Picotti PM, Malatesta M, Cisterna B.
Mitochondrial Features of Mouse Myoblasts Are Finely Tuned by Low Doses of Ozone: The Evidence In Vitro.
Int J Mol Sci. 2023 May 17;24(10):8900. doi: 10.3390/ijms24108900.
38) M. Bonetti, G.M. Ottaviani, L. Simonetti, G.A.Pellicanò, F. Bonetti and M.Muto
Chapter: Treatment of Low-Back Pain with Oxygen-Ozone Therapy
In: Hernia Updates. Ed: Intechopen, Published: June 20th, 2023, pagg 245-267
DOI: 10.5772/intechopen.1001902
39) M. Moretti, G. Bragaglio, G. Guarino, I. Marchina, GM. Ottaviani, G. Tabaracci and M. Bonetti
Our experience in the treatment of rhizarthrosis with oxygen-ozone therapy
Journal of Orthopedics 2023 Sep-Dec; 15(3): 1-6
40) Inguscio CR, Cisterna B, Lacavalla MA, Donati F, Angelini O, Tabaracci G, Malatesta M.
Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma.
Eur J Histochem. 2023 Oct 10;67(4):3879. doi: 10.4081/ejh.2023.3839.
41) Tricarico G, Travagli V.
Comment on Barczyk et al. Potential Clinical Applications of Ozone Therapy in Dental Specialties-A Literature Review, Supported by Own Observations. Int. J. Environ. Res. Public Health 2023, 20, 2048.
J Environ Res Public Health. 2023 Dec 8;20(24):7154. doi: 10.3390/ijerph20247154.
42) Inguscio CR, Cisterna B, Carton F, Barberis E, Manfredi M, Malatesta M.
Modifications of Blood Molecular Components after Treatment with Low Ozone Concentrations.
Int J Mol Sci. 2023 Dec 6;24(24):17175. doi: 10.3390/ijms242417175.
43) Sallustio F. Campobasso N, et al. (2023).
Ozone Therapy in Wound Care.
In: Maruccia, M., Papa, G., Ricci, E., Giudice, G. (eds) Pearls and Pitfalls in Skin Ulcer Management. Springer, Cham. https://doi.org/10.1007/978-3-031-45453-0_49
44) E. Maetzke
Treatment of a dental element with isolated periodontitis using oxygen-ozone therapy. a case report
Eur J Musculoskel Dis 2024 May-Aug;13(2).
45) Olga Di Fede, Gaetano La Mantia, Carmine Del Gaizo, Rodolfo Mauceri, Domenica Matranga, Giuseppina Campisi
Reduction of MRONJ risk after exodontia by virtue of ozone infiltration: A randomized clinical trial
Oral Diseases. 2024;30:5183–5194
46) Inguscio CR, Carton F, Cisterna B, Rizzi M, Boccafoschi F, Tabaracci G, Malatesta M.
Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro.
Eur J Histochem. 2024 Sep 9;68(3):4106. doi: 10.4081/ejh.2024.4106.
47) Vagaggini, L. Paoli, and L. Zanasi
Lumbar synovial cyst treated with oxygen-ozone therapy: case report
Eur J Musculoskel Dis 2024 May-Aug;13(2):
48) Tabaracci, M. Moretti, G.M. Ottaviani, A.M. Repossini, and M. Bonetti
Combined treatment of rhizathrosis with local infiltrations of oxygen-ozone and topical applications of alfa-lipoic acid, capsaicin, cannabidiol, beta-caryophyllene, and myrrh g.
Eur J Musculoskel Dis 2024 May-Aug;13(2)
49) M.Bonetti et al.
Trattato di Ossigeno-Ozono terapia
Ed Piccin Padova 2024
ISBN 978-88-299-3468-3
50) F. Albertini
A case of meralgia paresthetica treated with ozone therapy
Journal of Orthopedics 2024 May-September; 16(2): Ahead of Print
51) Davidovic K, Cotofana S, Heisinger S, Savic S, Alfertshofer M, Antonić T, Jovanović S, Ercegovac M, Muto M, Jeremić D, Janićijević A, Rasulić L, Janošević V, Šarić L, Chua D, Masulovic D, Percutaneous Computed Tomography-Guided Oxygen-Ozone (O(2)O(3)) Injection Therapy in Patients with Lower Back Pain-An Interventional Two-Year Follow-Up Study of 321 Patients.
Maksimović R.Diagnostics (Basel). 2023 Nov 2;13(21):3370. doi: 10.3390/diagnostics13213370.
Società Scientifica riconosciuta dal Ministero della Salute ai sensi della L. 8 marzo 2017, n.24
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